Complement activation in acne vulgaris: in vitro studies with Propionibacterium acnes and Propionibacterium granulosum

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Comparative studies of porphyrin production in Propionibacterium acnes and Propionibacterium granulosum.

Porphyrin production by Propionibacterium acnes and that by Propionibacterium granulosum were compared. Porphyrin synthesized by both organisms was identified as coproporphyrin III on the bases of absorption and fluorescence spectra and behavior on paper chromatography and thin-layer chromatography. Quantitative, rather than qualitative, differences in production were found between these organi...

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In vitro antimicrobial susceptibility patterns of Propionibacterium acnes isolated from patients with acne vulgaris.

INTRODUCTION Propionibacterium acnes has been implicated in the development of acne vulgaris. Rampant use of topical and systemic antibiotics for acne vulgaris has led to resistance due to selective pressure. This study aimed to determine antibiotic resistance of P. acnes. METHODOLOGY A total of 102 samples were collected from acne lesions and cultured onto sheep's blood agar and brain-heart ...

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IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes in patients with acne vulgaris.

IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes were determined in sera from patients with mild, moderate or severe acne and from a control group. Titres specific to S. epidermidis were all within the same range and did not differ between groups. The titres of IgG subclasses to specific to P. acnes did vary between groups. IgG1 and IgG3 were significantly highe...

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Susceptibility of Propionibacterium acnes isolated from patients with acne vulgaris to zinc ascorbate and antibiotics

PURPOSE The in vitro antimicrobial activity of ascorbic acid derivatives against Propionibacterium acnes was tested either alone or in combination with a variety of antimicrobial agents, and their fractional inhibitory concentration index was determined using checkerboard tests. The antimicrobial effectiveness of zinc ascorbate in the treatment of acne vulgaris, either alone or in combination w...

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Propionibacterium acnes.

Propionibacterium acnes, a common skin organism, is most notably recognized for its role in acne vulgaris. It also causes postoperative and device-related infections and has been associated with a number of other conditions such as sarcoidosis and synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO), although its precise role as a causative agent remains to be determined. Propionibact...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1978

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.22.2.523-529.1978